"increasing lifespan" notwithstanding, you don't have to remove the AT unit and sensors to turn it off. You can globally or even selectively turn off autotune by simply putting in a zero AFR map into the unit. That is, the AT software sees 0's as a signal to skip over those cells and not autotune there at all.
You have the right idea with ride, accept trims, ride. Once refined, your options are to disable autotune like above, or to reduce the enrichment/enleanment limits. I recommend the latter because you can reduce hunting (which honestly is not a big problem on these units once you are zeroed in), while allowing for some variation in environmental factors. The thing to note is if you have anrich/leanment limits of say +/-5, and you see values of +/-5 in your trim map, you should either accept the trim and retune, or widen your limits because you may be out of tune in those cells since the software is maxed out.
Finally, autotune works well in cells that can be easily reached in a steady state. 0% throttle at anything above idle, for example is not a column you want to turn on autotune for- it will just be wrong and can cause major popping. in fact, most maps I've seen have a zero AFR in the 0% column for this very reason.
2011 Victory Kingpin 8-Ball
Tach / Dual front discs with Vesrah JL pads / Penske shock / S&S Intake / PCV & autotune / RPW Thor exhaust with homemade custom baffle / Tsukayu leather "Strong" bags / Avon Cobra *Radials* / Ness Vegas Peg Conversion / Ness Vegas driver's seat / Custom T-Apes from BR Custom Cycles